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Can those food sensitivity tests really help prevent discomfort on your daily run?
Can those food sensitivity tests really help prevent discomfort on your daily run? (Photo: Rob and Julia Campbell)

Should You Take a Food-Sensitivity Test?

Over-the-counter tests promise to cure your food-related ailments, but some question whether they work, and others warn they might do more harm than good. I decided to give one a shot to find out.

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Can those food sensitivity tests really help prevent discomfort on your daily run?
(Photo: Rob and Julia Campbell)

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When I run fast, I have to poop. It鈥檚 pretty much a given, and it鈥檚 quite maddening. Every PR effort I make is thwarted by a stop in a Porta-Potty, and while I鈥檝e always made it to that blue plastic beacon of relief in time, it haunts me to think about the day聽I won鈥檛.

Although I have no non-running-related symptoms, I鈥檝e always suspected I likely have some sort of food sensitivity. My track buddies guessed it was gluten, which wasn鈥檛 too surprising: gluten-free mania has swept the nation over the past few years, and a published in the International Journal of Sport Nutrition and Exercise Metabolism reported that 41 percent of nonceliac athletes had tried a gluten-free diet. published in Medicine and Science in Sports and Exercise, however, found that athletes saw no improvement after eliminating gluten. That was my experience: I cut gluten from my diet for two weeks yet was still doing repeats to and from the restroom.

So, if not gluten, then what? I wondered. I thought about doing a two-week elimination diet鈥攁 medically recommended protocol where those with suspected food intolerance鈥攂e it an allergy or sensitivity鈥攔emove an item of food from their diet for 14 days and then reintroduce it to see if they have a bad reaction. But trying that with every single food would take months, maybe even years. Wouldn鈥檛 it be great if there were some sort of quick test you could take instead?

Well, now there is鈥攐r at least there claims to be. Over-the-counter food-sensitivity testing kits, which measure the body鈥檚 inflammatory response to foods via a quick finger-prick blood test, are gaining popularity, especially with naturopathic doctors and wellness coaches. I wanted to try one for myself.

First, I spoke to a few allergists, most of whom weren鈥檛 convinced that these tests are useful. Some said they might even be dangerous. Sensitivities and allergies are very different鈥攅specially when it comes to food. As anyone with a peanut allergy can attest, food allergies are often life-threatening, whereas sensitivities are annoying and potentially embarrassing.

Over-the-counter food-sensitivity testing kits are gaining popularity, especially with naturopathic doctors and wellness coaches.

In fact, 鈥渇ood sensitivity鈥 is a term that had almost no meaning until 2012, when in the American Journal of Gastroenterology found a subset of the population that wasn鈥檛 celiac but did have clinically significant gastrointestinal reactions to wheat. After publication, nonceliac wheat sensitivity became a recognized clinical condition. Many聽doctors say it opened the door for other food sensitivities that may or may not be rooted in anything more than pseudoscience. 鈥淚t鈥檚 an incredibly vague, nondescript term that has no real definition,鈥 says Stewart Carr, an assistant professor of pediatrics at the University of Alberta and a practicing allergist and immunologist. 鈥淲hen the companies marketing these tests聽use sensitivity instead allergy on one of their labels, they do it because it they know it doesn鈥檛 really mean anything.鈥

Traditional allergy tests, on the other hand, are clear in what they measure: a hypersensitive immune response to specific triggers. Most allergists use an immunoglobulin E (IgE) test, which measures the level of the antibody IgE in one鈥檚 blood鈥攁 marker of an allergic reaction鈥攁nd do so in conjunction with skin-prick testing and an oral food challenge: a doctor has a patient try a food in the office so medical help is close at hand if they go into anaphylaxis. In other words, real allergy tests are expensive, labor intensive, and definitely not something you can do conclusively at home.

Over-the-counter food-sensitivity tests, however, are almost always immunoglobulin G (IgG) tests. This test, in contrast, examines a cell鈥檚 inflammatory responses to different foods. The idea is that if a substance triggers inflammation, it鈥檚 probably best if you avoid that food. 鈥淲e鈥檙e looking at different cells than the cells that are involved in allergies,鈥 says Ethan DeMitchell, vice president of Oxford Biomedical Technologies, a company that patented and developed a test known as an MRT, or a mediator release test, which measures the presence of cells that release chemicals that prompt a non-allergic inflammatory response to food. While MRT is also used as a means to test food sensitivity, it is distinct from IgG tests.

Jan Patenaude, a Hawaii-based registered dietitian, says that MRT tests have produced 鈥渄ramatic, quick results鈥 among some of her clients. 鈥淲e see people get better in ten days,鈥 she adds. Patenaude has had luck treating runners, too鈥攑eople with nebulous GI problems like mine.

In talking about IgG tests, Carr argues that a cell鈥檚 inflammatory reaction to foods can actually be a marker of tolerance, not intolerance. This is because your body naturally produces antibodies when it detects a foreign protein. The test reads this as inflammation, but the antibodies are actually 鈥渄riving your body into a state of tolerance,鈥 he says, adding that 鈥渢his is a normal and healthy response.鈥


Since most over-the-counter food sensitivity tests are IgG, as opposed to MRT, I decided to order an IgG test from Washington-based Food Safe. When it arrived, I pricked my finger, smeared blood across five spots on a single piece of paper, and returned the blood-stained cards via overnight mail to Food Safe. Two weeks later, a packet of results arrived: apparently, I鈥檓 sensitive to dairy and eggs, two things I eat daily. Interestingly, it indicated that I had no reaction to peanuts or oysters, which I鈥檝e had actual allergic responses to in the past.

Patenaude had warned me that dairy is an incredibly common food sensitivy, and that eliminating it often does wonders for her clients. While I was bummed to ditch my daily yogurt and half-and-half, I was hopeful that maybe I鈥檇 found my trigger.

On a Monday morning, I opened a can of coconut milk and sloshed a bit into my coffee. I looked wistfully at the carton of eggs in my fridge. The day went on, and I felt normal, if not a little hungry. Tuesday was the real test, since I do speed work that night. I laced up my shoes, ready to fly. But by interval three, I was feeling the familiar intestinal rumblings that usually mean, Go directly to your nearest bathroom.

Allergists aren鈥檛 convinced that these tests are useful, and some say they might even be dangerous.

The rest of the dairy- and egg-free week passed like most others: Some days I ran without incident. Other days, things were iffier. If there was a change, it was negligible.

It's possible that I should have done an MRT test instead of IgG. Patenaude told me that before she did her own MRT testing, she鈥檇 had no real health complaints. But when she cut out the foods she was reactive to according to her test, the aches and pains that she鈥檇 hardly noticed before went away. 鈥淥ften people just don鈥檛 recognize their symptoms; they think the way they鈥檙e feeling is just normal,鈥 she says.

That鈥檚 an appealing promise鈥攖o wake up free of the symptoms you never even knew you had. Alas, that was not the case for me after my IgG test. I still struggled to sleep at night, which has always been an issue for me, and I still had that niggling pain in my left knee, a constant companion of mine since a cycling mishap ten years ago. I still sniffled at random times from nebulous allergies as well.

A week later, feeling entirely the same if not a little sick of coconut milk, I returned to adding cream to my coffee and having eggs for breakfast. I sat down at my computer, waiting for cramps or some sort of reaction to hit. It never happened. That night I went for a run and felt fine.


Am I really sensitive to dairy? Probably not. 鈥淲hen you鈥檙e testing for everything, it鈥檚 really easy to get a false positive,鈥 says Purvi Parikh, an allergist and immunologist with the . My IgG test looked at well over 100 foods: the more you test, the more likely it is that something will come back flagged for a variety of innocuous reasons鈥攁 false positive.

Parikh also worries about the false negatives. If someone suspects an allergy and does an at-home test to avoid a doctor visit, it could tell them that peanuts or shellfish or other things they鈥檙e highly allergic to are fine, since it鈥檚 testing the IgG response and not the true indicator of an allergy鈥擨gE. And that鈥檚 dangerous, since food allergies can be lethal. 鈥淚f you suspect a true allergy, stop eating the food until you鈥檙e tested,鈥 says Parikh. 鈥淵ou need to be equipped with proper medication.鈥

鈥淔ood-sensitivity companies are really just taking your money.鈥

Mostly, though, Carr just feels like these tests are a waste of money. After all, there鈥檚 a totally free way to determine if a food is making you feel bad: eliminate it and then see how you feel. 鈥淔ood-sensitivity companies聽are really just taking your money,鈥 he says of IgG test specifically. 鈥淎nytime you see a disclaimer on a medical test saying that the test is not meant to diagnose or replace a doctor, you can just stop there.鈥 (My test鈥檚 exact warning, in tiny print: 鈥淭his test does not detect IgE based immediate type food allergies.鈥)

And my fecal urgency, which is just as much of an issue as when I wasn鈥檛 eating dairy and eggs, may not even be food related. Sophie Balzora, a gastroenterologist and assistant professor of medicine at NYU Langone Medical Center, says a mix of factors can cause runner鈥檚 diarrhea. The jostling motion of running plus the decrease in blood flow from the GI tract may be the two biggest culprits. Unfortunately, those two things happen no matter what you eat (though high-fiber foods can make symptoms worse).

While it鈥檚 a bummer not to have any clear-cut way to relieve my GI symptoms for now, I鈥檓 choosing to look on the bright side: I clock some of my fastest times on those mad dashes to the restroom.

Corrections: (04/29/2025) A previous version of this story misrepresented the differences between IgG and MRT tests in several instances. 国产吃瓜黑料 regrets the error.
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Lead Photo: Rob and Julia Campbell

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